The objectives of this study are to evaluate efficacy and safety of artificial saliva containing cumin and ginger extract in head and neck cancer patients with xerostomia.
Age more than 18 years
Head and neck cancer with xerostomia
6 months post radiation
Willing to participate in this study
Sialolith or Sjogren's syndrome
Uncontrolled cancer
Using artificial saliva more than 2 weeks
Taking Pilocarpine or cevimeline more than 2 weeks
Parallel
Artificial saliva containing cumin and ginger extract
Other interventionArtificial saliva containing cumin and ginger extract in spray bottle
Placebo
Other interventionPlacebo containing composition close to the test group without cumin and ginger extract in spray bottle
Amount of saliva
Spit saliva to the bottle for 5 min
Acid and base characteristic of saliva
Spit saliva to the bottle, then take 1 piece of pH strip and dip it into the saliva for 30 seconds. Compare the color of the dipped pH strip to the color chart on pH strip box. The result shows value at pH 1-14.
Xerostomia questionnaires
Assessment xerostomia symptom by patient (scoring 1 to 10 point (low to high xerostomia severity)).
Oral Mucositis Grading Scale
Evaluate oral mucosa by physician (scoring 0 to 4 point (none to life-threatening)).
Adverse reaction: Skin reaction
Found or not found
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options:
