About this trial
The overall objective of this study is to improve the standard of care of critically ill pediatric patients. The specific aims are to describe the clinical profile and outcomes of all admissions to Asian pediatric ICUs, determine the risk factors associated with poor outcomes, determine quality indicators for benchmarking ICU performance across sites and develop and train artificial intelligence algorithms to predict mortality, length of ICU stay and resource utilization.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
All patients admitted to the pediatric ICUs of participant hospitals
Disqualifiers
No consent
Trial population
Though the main methodology is recruitment of all pediatric ICU admissions, a pre-determined random sampling protocol is allowed for sites with limited in resources for recruitment and data collection. This protocol may involve recruitment of all admissions for 1year (52 weeks), all admissions for 1 month per quarter over 1 year (16 weeks), all admissions for 1 week per month over 1 year (12 weeks), all admissions for 2 weeks per quarter over 1 year (8 weeks) or all admissions for 1 week for quarter over 1 year (4 weeks) - this will be declared at the start of the study by each participating site before recruitment begins. This strategy will allow us to include sites with and without sufficient resources to be represented in this study.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Mortality
ICU mortality and time based mortality
Secondary outcomes
Ventilator duration
Ventilator duration and ventilator free days to account for mortality as competing outcome
ICU duration
ICU duration and ICU free days to account for mortality as competing outcome
Nosocomial infections
Including catheter related blood stream infection, catheter associated urinary tract infection hospital/ventilator associated pneumonia
Accidental extubations
Unplanned extubations
Other outcomes
Resource utilisation
Including ICU bed, ventilator and other ICU support utilisation. Hospital costs.
Cardiopulmonary resuscitation
CPR or code blue activation within the ICU
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
KK Women's and Children's Hospital
Lead sponsor
King Chulalongkorn Memorial Hospital
Collaborator
Tengku Ampuan Rahimah Hospital
Collaborator
King Abdullah Specialized Children's Hospital
Collaborator
Children's Hospital 2
Collaborator
University Malaysia Medical Centre
Collaborator
Saiful Anwar Hospital
Collaborator
Murni Teguh Memorial Hospital
Collaborator
Siriraj Hospital
Collaborator
Harapan Kita Women and Children Hospital
Collaborator
Vicente Sotto Memorial Medical Center
Collaborator
Hong Kong Children's Hospital
Collaborator
Ramathibodi Hospital
Collaborator
Aga Khan University
Collaborator
Aichi Children's Health and Medical Center, Japan
Collaborator
Hospital Sultanah Aminah Johor Bahru
Collaborator
Children's Hospital of Chongqing Medical University
Collaborator
Prof IGNG Ngoerah Hospital
Collaborator
Penang Hospital, Malaysia
Collaborator
Vietnam National Children's Hospital
Collaborator
Hospital Pakar Kanak-kanak UKM
Collaborator
National University Hospital, Singapore
Collaborator
Queen Elizabeth Hospital, Hong Kong
Collaborator
Shanghai Children's Medical Center
Collaborator