Assesment of Epidural Platelet-Rich Plasma (PRP) Injection During Uniportal Endoscopic Lumbar Disc Herniation Excision on Residual Neuropathies

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche

About this trial

The aim of this study is to assess neuropathic pain in the lower limb at 6 months post-operation in patients who have undergone surgery for a lumbar disc herniation using single-port endoscopic discectomy combined with an epidural PRP injection.

This study is based on the hypothesis that intraoperative epidural administration of PRP during discectomy may improve healing, reduce nerve inflammation and potentially minimise post-operative pain and complications.

Participants will perform an epidural PRP injection and questionnaires as part of this research.

Eligibility criteria

Qualifiers

Patients, male or female, aged ≥ 18 and ≤ 55

Patients with a diagnosis of a single-level lumbar disc herniation confirmed by MRI

Patients in whom conservative treatment has failed for at least 6 weeks

Patients for whom monoportal endoscopic lumbar disc herniation excision is indicated

Disqualifiers

Patients with a history of lumbar spine surgery or epidural injection

Patients with progressive neurological deficits or cauda equina syndrome

Patients with coagulopathy or systemic hematological disorders

Patients with an active infection or autoimmune disease

Trial design

Treatments tested in this trial

  • Uniportal endoscopic lumbar disc herniation removal

Treatment groups

50 Participants
are divided into 1 treatment group