About this trial
The aim of this study is to assess neuropathic pain in the lower limb at 6 months post-operation in patients who have undergone surgery for a lumbar disc herniation using single-port endoscopic discectomy combined with an epidural PRP injection.
This study is based on the hypothesis that intraoperative epidural administration of PRP during discectomy may improve healing, reduce nerve inflammation and potentially minimise post-operative pain and complications.
Participants will perform an epidural PRP injection and questionnaires as part of this research.
Eligibility criteria
Qualifiers
Patients, male or female, aged ≥ 18 and ≤ 55
Patients with a diagnosis of a single-level lumbar disc herniation confirmed by MRI
Patients in whom conservative treatment has failed for at least 6 weeks
Patients for whom monoportal endoscopic lumbar disc herniation excision is indicated
Disqualifiers
Patients with a history of lumbar spine surgery or epidural injection
Patients with progressive neurological deficits or cauda equina syndrome
Patients with coagulopathy or systemic hematological disorders
Patients with an active infection or autoimmune disease
Trial design
Treatments tested in this trial
- Uniportal endoscopic lumbar disc herniation removal