Assesment of Upper Egypt Experience in Autologous Bone Marrow Transplantation of Patients With Hematological Malignancies: A Cohor Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorAssiut University

About this trial

Autologous hematopoietic stem cell transplantation (ASCT) is an important treatment for eligible patients with hematological malignancies, particularly multiple myeloma and relapsed lymphoma. Although advances in transplantation have improved outcomes, complications such as infections, febrile neutropenia, mucositis, delayed engraftment, organ toxicity, and relapse remain significant. This study aims to evaluate clinical outcomes and patient satisfaction after ASCT and identify factors associated with favorable or unfavorable transplant outcomes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patients (≥18 years) with a confirmed diagnosis of a hematological malignancy.

Patients undergoing their autologous hematopoietic stem cell transplantation (ASCT).

willingness to participate in the study

Disqualifiers

Patients undergoing allogeneic hematopoietic stem cell transplantation.

Patients with uncontrolled active infection or severe organ dysfunction that contraindicates transplantation.

Patients with incomplete clinical data or who withdraw consent during the study period.

Trial population

All consecutive adult patients with hematological malignancies who underwent autologous hematopoietic stem cell transplantation at the Bone Marrow Transplantation Unit, Assiut University Hospitals, during the study period and fulfilled the eligibility criteria.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

123 Participants
are grouped into 1 trial group
Group A: Autologous bone marrow transplant patients

Trial outcomes

Primary outcomes

1

PFS

Clinical outcome of autologous hematopoietic stem cell transplantation, including overall survival (OS) and Progression-Free Survival (PFS).

Time frame
through study completion, an average of 2 year

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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