Health TrialsbyHealthPanel

Assessment of D-dimer and CRP for Cardiovascular Risk Prediction in Hemodialysis Patients

ConditionEnd Stage Renal Disease on Dialysis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

This study aims to assess whether two blood markers - C-reactive protein (CRP) and D-dimer - can help predict cardiovascular complications in patients undergoing regular hemodialysis. Cardiovascular disease is a common and serious problem in dialysis patients, and early detection is important.

the study will include 100 adult patients from the Hemodialysis Unit at Assiut University Hospital. Participants will be divided into two groups: those with and those without known heart disease. Each participant will have a one-time blood test to measure CRP and D-dimer levels. In addition, an electrocardiogram (ECG) will be done once to check for signs of heart problems.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged ≥18 years

Disqualifiers

Acute or recent infection (within the past 4 weeks)

Trial population

Hemodialysis patients treated at the Hemodialysis Unit of Assiut University Hospital, including those with and without documented cardiovascular disease.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

  • C-Reactive Protein (CRP) Test

    Diagnostic test

    Blood samples will be collected once from all participants to measure CRP levels

  • D-dimer Test

    Diagnostic test

    D-dimer levels will be assessed once to evaluate thrombotic risk.

  • Electrocardiogram (ECG)

    Diagnostic test

    A standard 12-lead ECG will be performed once per participant to assess cardiovascular status

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: Hemodialysis Patients without Cardiovascular Disease3 interventions
Group B: Hemodialysis Patients with Cardiovascular Disease3 interventions

Trial outcomes

Primary outcomes

1

Serum CRP level among hemodialysis patients

To assess the level of serum CRP in hemodialysis patients with and without cardiovascular disease and compare values between the two groups to explore possible associations

Time frame
At baseline (one-time measurement)
2

Plasma D-dimer level among hemodialysis patients

To assess the level of plasma D-dimer in hemodialysis patients with and without cardiovascular disease and compare values between the two groups to explore possible associations.

Time frame
At baseline (one-time measurement)

Secondary outcomes

1

Presence of cardiovascular abnormalities on ECG

To assess cardiovascular status of hemodialysis patients using a standard 12-lead ECG and record the presence of abnormal findings

Time frame
At baseline (one-time measurement)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: