Assessment of Electromyographic Activity in the Quadriceps and Hamstrings of the Operated Limb Versus the Unaffected Limb in Patients Who Have Undergone ACL Surgery, With and Without Post-operative AMI - an Exploratory Study

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche

About this trial

Traumatic injuries to the knee joint, such as an anterior cruciate ligament tear, can compromise the ability of the muscle at the front of your thigh-known as the quadriceps-to contract voluntarily, despite the anatomical integrity of the nerve and muscle structures responsible for contraction. This phenomenon, commonly known as 'arthrogenic motor inhibition' (AMI), is a major limiting factor for recovery and rehabilitation following an anterior cruciate ligament tear, as well as a potential cause of functional disability if left undiagnosed and untreated. Indeed, motor inhibition that persists during the early months of rehabilitation could lead to under-activation of the quadriceps and over-activation of the hamstrings (the muscles at the back of your thigh).

It is of interest to assess, during the rehabilitation phase, the contraction capacity of the various quadriceps and hamstring muscles in the operated limb compared with the unaffected limb in patients who have undergone anterior cruciate ligament surgery and who experience post-operative motor inhibition, and in patients who have undergone anterior cruciate ligament surgery but do not experience post-operative motor inhibition. This is why this study has been initiated.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient who has undergone ACL surgery at least 3 weeks ago

Patient with no severe knee inflammation: stroke test ≤ 1+ and pain ≤ 3/10 (EN) at rest

Patient with a Tegner score ≥ 5

Patient with a Marx score ≥ 8

Disqualifiers

Patient with a previous injury or surgery to the same or opposite knee

Patient with a multi-ligament injury

Patient with an AMI > grade 2b (Sonnery-Cottet et al. classification)

Patient with a BMI > 30

Trial design

Design model

Single group

Treatments tested in this trial

  • Electromyography

    Behavioral

    Surface EMG of the quadriceps (vastus medialis, vastus lateralis and vastus longus) and the semimembranosus and biceps femoris muscles of the hamstrings on both the affected and unaffected sides, to objectively assess quadriceps inhibition.

Treatment groups

40 Participants
are divided into 1 treatment group
Group A: ACL ArmExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

EMG activity

The average amplitude of EMG activity in the VM (Vastus Medialis) is assessed using the Root Mean Square (RMS) value, which is expressed in millivolts (mV). The RMS is recorded using surface electrodes placed on the vastus medialis. The primary outcome measure (activation deficit) is the absolute difference in RMS between the operated leg and the unaffected leg.

Time frame
Month 3

Secondary outcomes

Other outcomes

Sponsors and contacts

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