Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors

ConditionTumors
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorM.D. Anderson Cancer Center

About this trial

To learn about the symptoms and changes our patients experience while receiving treatment for sinonasal or nasopharyngeal cancer

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Previously untreated patients with or suspected to have sinonasal malignancy or nasopharyngeal malignancy diagnosis based on either outside pathology report or MD Anderson pathology report.

Age ≥ 18 years

Plan to obtain the majority of treatment at MDACC including surgery and radiotherapy

Ability to understand and willingness to sign written informed consent

Disqualifiers

History of the previous solid or liquid malignancies, apart from skin cancers treated with local therapy.

Existing neurocognitive impairment that is not the result of sinonasal and nasopharyngeal cancers or is treatment.

Previous treatment for sinonasal or nasopharyngeal carcinomas, apart from biopsy.

Trial population

M D Anderson Cancer Center

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Standard of Care

    Behavioral

    Standard of care assessment of their function including pituitary hormone lab draws, audiogram hearing test, eye exam, teeth and jaw exam (in trismus clinic) and speech and swallowing evaluation

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

MD Anderson Symptom Inventory Head and Neck Module (MDASI-HN)

MD Anderson Symptom Inventory Head and Neck Module (MDASI-HN) is a disease specific PRO instrument validated for patients with head and neck cancer. It is the most commonly utilized instrument in the head and neck cancer population, of which sinonasal and nasopharyngeal tumors are disease subsites. Score scale from 0 (symptom has been present) to 10 (the symptom was as bad as you can imagine it could be)

Time frame
through study completion; an average of 1 year

Secondary outcomes

Other outcomes

Sponsors and contacts

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