Health TrialsbyHealthPanel

Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars

ConditionIrreversible Pulpitis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15-30
SponsorFuture University in Egypt

About this trial

Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • pulpotomy

    Procedure/Surgery

    removal of the coronal pulp tissue and preservation of the radicular portion to ensure continuation of growth and vitality of tooth structure

Treatment groups

45 Participants
are divided into 3 treatment groups
Group A: hydroxyapatiteExperimental treatment 1 intervention
Group B: L-PRFExperimental treatment 1 intervention
Group C: L-PRF combined with Nano-hydroxyapatiteExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

post operative Pain assessment

Pain evaluations were conducted preoperatively with numerical rating scale ( a verbal or writing determination of a pain level on a scale from 0 to 10, in which 0 represents no pain and 10 represents excruciating pain .

Time frame
6, 12, 24, 72hours and 7 days after treatment

Secondary outcomes

1

Dentine bridge formation

evaluating the thickness of dentine bridge formed after the procedure by comparing immediate post operative CBCT with the one year follow up scans

Time frame
12 months post operative

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Future University in Egypt

Lead sponsor

Source ClinicalTrials.gov
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