Assessment of Process and Outcome of Protocol-based Weaning From Mechanical Ventilation in the Medical Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19-99
SponsorSamsung Medical Center

About this trial

This is a prospective, single-center, observational study to describe characteristics of weaning process and factors associated with duration of weaning and its outcomes in all consecutive adult (aged 19 years and older) patients receiving mechanical ventilation for at least two calendar days in medical intensive care units since November 2017. Details of the patients' weaning process and spontaneous breathing trial (SBT) in addition to clinical, laboratory, and outcome data will be collected in a specified format on the day of the assessment by respiratory care practitioners.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All consecutive adult patients receiving mechanical ventilation for at least two calendar days in medical intensive care units

Disqualifiers

None

Trial population

Adult patients receiving mechanical ventilation for at least two calendar days in medical intensive care units

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Successful weaning

Extubation without death or reintubation within the next 7 days of spontaneous breathing trial or discharge from intensive care unit without invasive mechanical ventilation (MV) within 7 days, whichever comes first for intubated patients and as spontaneous ventilation through tracheostomy without any MV during 7 consecutive days or discharged with spontaneous breathing, whichever comes first for patients with tracheostomy after the first separation attempt

Time frame
6 months from MV
2

Weaning outcomes by the Weaning Outcome according to a New Definition (WIND) classification

Group 1 (short weaning), the first attempt result in the termination of the weaning process within 1 day Group 2 (difficult weaning), the weaning process is completed after more than 1 day but in less than 1 week after the first separation attempt Group 3 (prolonged weaning), the weaning process is still not terminated 7 days after the first separation attempt.

Time frame
6 months from MV

Secondary outcomes

Other outcomes

Sponsors and contacts

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