In the current literature, it has been widely demonstrated that the extend of coronary atherosclerotic burden is associated with adverse long-term outcomes. Little is known about the impact of atheroma burden and either myocardial reperfusion and short-term outcomes after ST-segment elevation myocardial infarction (STEMI). Several angiographic scores have been used to measure the extend and severity of coronary atheroma. The SYNTAX score and the Gensini score have been shown to be independent predictors of cardiovascular events and mortality in stable coronary artery disease as well as in myocardial infarction.
This research therefore aims to assess the impact of overall coronary atherosclerotic burden, measured by two angiographic scores (SYNTAX score and Gensini score), both before and after primary percutaneous angioplasty, in patients with STEMI according to different clinical subgroups.
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Patients presenting with STEMI and treated with primary PCI (pPCI) at the University Hospital of Nancy between 2003 and 2023. STEMI was defined as follows: 1. continuous chest pain lasting at least 20 min 2. ST-segment elevation ≥1 mm in ≥2 contiguous leads on a 12-lead electrocardiogram or left bundle branch block and (3) treatment within 24 h of pain onset.
Cohort
Retrospective
Not listed
All-cause mortality
all-cause mortality at 45 days, 1 year and 2 years
Recurrent acute coronary syndrome
Recurrent acute coronary syndrome at 1-year
All-cause mortality in patients with STEMI related to out-of-hospital cardiac arrest or cardiogenic shock
All-cause mortality at 45 days, 1 year and 2 years in patients with STEMI related to out-of-hospital cardiac arrest or cardiogenic shock
Recurrent acute coronary syndrome in patients with STEMI related to out-of-hospital cardiac arrest or cardiogenic shock
Recurrent acute coronary syndrome at 1 year in patients with STEMI related to out-of-hospital cardiac arrest or cardiogenic shock
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