Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorIstanbul University - Cerrahpasa

About this trial

This prospective observational study aims to evaluate renal perfusion in adult patients undergoing elective minimally invasive abdominal surgery. Renal perfusion will be assessed using two non-invasive monitoring techniques: Doppler ultrasonography-derived Renal Resistive Index (RRI) and Near-Infrared Spectroscopy (NIRS)-derived renal regional oxygen saturation (rSO₂).

Measurements will be obtained at predefined perioperative time points, including after induction of anesthesia, during pneumoperitoneum, before extubation, and during the early postoperative period. Perioperative changes in renal perfusion parameters will be analyzed and correlated with clinical variables such as intra-abdominal pressure, pneumoperitoneum duration, hemodynamic parameters, fluid administration, urine output, and postoperative renal function.

The study also aims to investigate the relationship between intraoperative renal perfusion changes and the development of postoperative acute kidney injury. The findings may contribute to improved perioperative monitoring and optimization of renal perfusion during minimally invasive abdominal surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18 to 80 years

Patients with ASA physical status I, II, or III

Patients undergoing elective minimally invasive abdominal surgery for any reason

Patients whose expected surgical duration is longer than 1 hour

Disqualifiers

Body mass index greater than 35 kg/m²

Severe respiratory system disease

Severe heart failure, NYHA class III-IV

Presence of a cardiac pacemaker or cardiac defibrillator implant

Trial population

Adult patients aged 18-80 years with ASA physical status I-III undergoing elective minimally invasive abdominal surgery at Istanbul University-Cerrahpaşa Faculty of Medicine. Patients will be prospectively evaluated for perioperative renal perfusion using Doppler ultrasonography and Near-Infrared Spectroscopy (NIRS).

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

51 Participants
are grouped into 1 trial group
Group A: Elective Minimally Invasive Abdominal Surgery Patients

Trial outcomes

Primary outcomes

1

Change in Renal Regional Oxygen Saturation Measured by NIRS

Renal regional oxygen saturation (rSO₂) will be measured bilaterally using Near-Infrared Spectroscopy (NIRS). NIRS values will be recorded at predefined perioperative time points.

Time frame
after endotracheal intubation, immediately before extubation, and 1 hour after extubation
2

Change in Renal Resistive Index

Renal Resistive Index (RRI) measured by Doppler ultrasonography at predefined perioperative time points. RRI will be calculated from peak systolic velocity and end-diastolic velocity obtained from renal interlobar or arcuate arteries.

Time frame
after endotracheal intubation, immediately before extubation, and 1 hour after extubation

Secondary outcomes

1

Relationship Between Renal Resistive Index and Renal Regional Oxygen Saturation

The relationship between renal Doppler ultrasonography-derived Renal Resistive Index (RRI) and NIRS-derived renal regional oxygen saturation (rSO₂) will be evaluated for the right and left kidneys at predefined perioperative measurement time points.

Time frame
after endotracheal intubation, immediately before extubation, and 1 hour after extubation

Other outcomes

Sponsors and contacts

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