Assessment of Right Ventricular Function After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

Echocardiographic Assessment:

Performed within 24h of PE diagnosis Conventional parameters: TAPSE, RV FAC, RV/LV ratio, tricuspid S', PASP STE parameters: RV free wall longitudinal strain (RVFWS), global longitudinal strain (GLS) if feasible All measurements averaged over 3 cardiac cycles (sinus) or 5 (AF)

Follow-up data:

ICU/hospital LOS Need for vasopressors/mechanical ventilation In-hospital and 30-day mortality

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults ≥18 years.

Confirmed acute PE (via CT pulmonary angiography).(4,6)

Echocardiography performed within 24 hours of diagnosis.

Disqualifiers

Pre-existing significant RV dysfunction (e.g., due to chronic pulmonary hypertension, cor pulmonale or congenital heart disease).

History of coronary artery disease.

Impaired LV systolic function, ejection fraction <50%.

Moderate to severe valvular heart disease.

Trial population

patients aged more than 18 years old with confirmed pulmonary embolism

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Primary (main): Composite of in-hospital mortality, ICU admission >7 days, or need for mechanical circulatory/ventilatory support.

Time frame
30 day follow up

Secondary outcomes

1

Secondary outcome: Each individual component; echocardiographic parameters as predictors.

Time frame
30 day follow up

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: