Assessment of the Diagnostic Performance of the Detection System and Establishment of an Intelligent and Rapid Triage Model

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorChina National Center for Cardiovascular Diseases

About this trial

The rapid triage of patients with acute chest pain remains an important issue in clinical practice. This study will establish a cohort of patients suspected of acute coronary syndrome (ACS) to construct a multi-marker dynamic combined intelligent triage model. This model will triage the risk of NSTEMI in patients with chest pain at their first visit. It will also stratify the risk of patients with chest pain using major adverse cardiovascular events (MACE) within 30 days as the endpoint.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18 years or above from China, regardless of gender;

Presence of symptoms such as chest tightness and chest pain, with the need to determine whether they are patients with acute coronary syndrome;

Ability to obtain informed consent.

Disqualifiers

- Patients with STEMI at the time of presentation;

Patients with a clear diagnosis after tests such as troponin;

Patients who have undergone major surgery or trauma within the past four weeks;

Pregnant women or patients with tumors undergoing radiotherapy or chemotherapy;

Trial population

Chinese population aged 18 years and above, regardless of gender, with symptoms of chest tightness and chest pain, who need to be confirmed as acute coronary syndrome patients.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Myocardial infarction

in patients suspected of NSTEMI, using the baseline (0 hours) and any one of the 1-3 hour points for the ZR iStar (POCT) hs-cTnI two-point method, combined with the time from typical chest pain to the visit, to establish a triage machine learning model for NSTEMI through the training cohort, and to establish a multi-marker dynamic combination intelligent triage model for risk stratification of chest pain patients.

Time frame
30 days to 6 months

Secondary outcomes

Other outcomes

1

High-sensitivity troponin

Validation of instruments and test kits by detecting high-sensitivity troponin levels using different platforms.

Time frame
Concentrated detection once every three months

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

China National Center for Cardiovascular Diseases

Lead sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Collaborator

This trial is not recruiting at the moment. You can still explore other options: