Association of a Digital Signature of Physical Activity and Sedentary Lifestyle With the Development of Multimorbidities in Chronic Diseases (eMOB)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorUniversity Hospital, Clermont-Ferrand

About this trial

Physical activity (PA) and sedentary lifestyle are determinants in the development of chronic diseases and associated quality of life alterations. PA levels are correlated with quality of life and morbidity in chronic lung disease (COPD), cardiovascular disease, diabetes, cancer, chronic inflammatory rheumatism, fibromyalgia and anxiety disorders. In these diseases, low-intensity PA often represents the main PA and the quantity of PA is correlated with health parameters.

This study aims to identify a typical profile (signature) in relation to the appearance of other chronic diseases, complications of your disease, from recording your physical activity and sedentary lifestyle by sensors evaluating very precisely the movements and taking into account the characteristics and disability related to your disease. The results of this study would therefore make it possible to identify this signature even before the appearance of complications or other diseases.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Inflammatory rheumatic disease(rheumatoid arthritis, spondyloarthritis) included in the RCVRIC cohort (CPP Sud-Est VI N° ID-RCB- A01847-40)

Pre-surgical knee and hip osteoarthritis (Evalmob) (ID-RCB N° 2019- A01017-50)

Major depressive disorder included in the FACE-DR cohort (CNIL agreement: DR- 2015-673) and Bipolar disorder included in the FACE-BD cohort (CPP Ile de France IX; January 18, 2010) of the Adult Psychiatry Department B

Type 2 diabetes included in the cohort of the sport medicine service "Rehabilitation T2" (CNIL agreement 0164)

Disqualifiers

Inability to practice physical activity

Pregnant or breastfeeding

Refusal to participate

Minors or adults under the protection of the law or under the protection of justice.

Trial design

Design model

Single group

Treatments tested in this trial

  • Accelerometer data

    Other intervention

    Patients will wear an accelerometer 3 times a year for 5 days (3 weekdays and 2 weekend days), the data will be collected

Treatment groups

700 Participants
are divided into 1 treatment group
Group A: Chronic diseasesOther 1 intervention

Trial outcomes

Primary outcomes

1

Occurrence of one additional comorbidity in patients with chronic diseases.

Association of a digital signature of PA and sedentary lifestyle with the development of at least one additional comorbidity over 4 years of follow-up.

Time frame
year 4
2

Digital signature of sedentary lifestyle and PA in patients with chronic diseases.

A sensor of movement will be worn by the patients for 5 days every 4 months during the study, to detect and quantify the physical activity and the sedentarity according to their intensity. This sensor will be accelerometer, allowing the acquisition of movements second by second. The analysis of the data from the sensors, the occurrence of a new comorbidity, the clinical data will allow to establish an algorithm to define a profile (digital signature) of occurrence of a new chronic disease.

Time frame
Year 4

Secondary outcomes

1

Occurence of multimorbidity in patients with chronic diseases.

Association of a sedentary and PA signature with the development over 4 years of one, two, three, or more comorbidities (multimorbidity).

Time frame
Year 1
2

Occurence of multimorbidity in patients with chronic diseases.

Association of a sedentary and PA signature with the development over 4 years of one, two, three, or more comorbidities (multimorbidity).

Time frame
year 2
3

Occurence of multimorbidity in patients with chronic diseases.

Association of a sedentary and PA signature with the development over 4 years of one, two, three, or more comorbidities (multimorbidity).

Time frame
Year 3
4

Occurence of multimorbidity in patients with chronic diseases.

Association of a sedentary and PA signature with the development over 4 years of one, two, three, or more comorbidities (multimorbidity).

Time frame
Yaer 4

Other outcomes

Sponsors and contacts

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