Association of Leucocyte Telomere Length With DPAS Score in Skin Aging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age29-61
SponsorDr.dr.Irma Bernadette, SpKK (K)
About this trial
The goal is to know the profile of photoaging based on clinical examination, Dermoscopic Photoaging Scale and leucocyte telomere length
The main questions of Research are:
* what is the profile of photoaging based on clinical examination results in skin aging * what is the profile of photoaging based on DPAS Score in skin aging * what is the profile of leucocyte telomere length in skin aging
Participants are female and male with the age of 29-31 years old and 59-61 years old. They will be examined by dermatovenereologist and will be photographed in 5 positions, they will get dermocopy on forehead, right cheek , left cheek, and chin, and their blood will be drawn about 10 mL in order to get the profile of leucocyte telomere length
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Female and Male (age 29-31 years old and 59-61 years old
signs of aging
Disqualifiers
pregnant or breastfeeding
have disease or genetic problem
Trial design
Design model
Parallel
Treatments tested in this trial
Leucocyte Telomere Length from blood draw
Geneticblood draw, PCR method to see leucocyte telomere length
Treatment groups
20 Participants
are divided into 2 treatment groupsGroup A: lifestyle counselingExperimental treatment 1 intervention
Group B: Clinical examinationExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
profile of leucocyte telomere length
profile of leucocyte telomere length in skin aging
Time frame
1 year2
Profile of skin examination from Glogau scale
Glogau type 1 (mild) is without wrinkles (Age of 28-35 years), type II (moderate) is wrinkles in motion (age of 35-50 years), III (advanced) with wrinkles at rest (age of 50-65 years), type IV (severe) is wrinkles all over the face (age of 60-75)
Time frame
1 year3
profile of skin examination with dermoscopic photoaging scale (DPAS)
skin aging is assessed from dermoscopic photoaging scale on dermoscopic images, looking at pigmentary changes, vascular changes, telangiectasis, wrinkles, actinic keratoses, and blackheads. There are four facial regions assessed in the DPAS score calculation, namely the forehead, right cheek, left cheek, and chin. The sum of the scores of the four regions is assessed based on 11 parameters, with a maximum final score of 44. The greater the score, the higher marks of skin aging
Time frame
1 yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
Dr.dr.Irma Bernadette, SpKK (K)
Lead sponsor
Indonesia University
Sponsor institution
Indonesia Medical Education and Research Institute
Collaborator
Source ClinicalTrials.gov