Association of Periodontal Inflammation on Immune Response in Wound Healing
ConditionInflammation of Mouth
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21-70
SponsorUniversity of Nebraska
About this trial
Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
non-restorable posterior tooth (molar/premolar) in need of extraction
Disqualifiers
systemic disease that effects inflammation
Trial population
Healthy adults ages 21-70 with non-restorable posterior tooth requiring extraction.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Dental Extraction
Procedure/SurgeryExtraction
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Inflammatory cells
Number of inflammatory cells present
Time frame
3 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov