Aswan Heart Centre - Egyptian Healthy Volunteers
ConditionGenetic Predisposition to Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMagdi Yacoub Heart Foundation
About this trial
To define the genotype of a healthy Egyptian cohort as a crucial step in determining the possible clinical implications of mutations detected in patients recruited in the registry.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Any adult Egyptian citizen subject that considers him/herself free of cardiovascular disease.
Disqualifiers
Individuals under 18 years of age
Known cardiovascular disease
Known collagen vascular disease
Individuals with communication difficulties, or who do not wish to participate
Trial population
1000 adult Egyptian citizen subjects that considers themselves free of cardiovascular disease.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Whole Genome Sequencing to compare healthy volunteers genome with that of cardiomyopathies patients.
Other interventionEgyptian patients and their family members diagnosed with different types hereditary cardiomyopathies.Healthy Egyptian individuals to provide the first of its kind resource on human genetic variation in Egyptians, which is essential for understanding the significance of detected variations in patients with inherited cardiovascular disease and their families.
Treatment groups
1,000 Participants
are divided into 2 treatment groupsGroup A: Control1 intervention
Group B: Cases1 intervention
Trial outcomes
Primary outcomes
1
Human genetic variation in Egyptians
To perform whole exome sequencing in 1000 healthy Egyptian individuals to provide the first of its kind resource on human genetic variation in Egyptians, which is essential for understanding the significance of detected variations in patients with inherited cardiovascular disease and their families.
Time frame
10 yearsSponsors and contacts
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Source ClinicalTrials.gov