About this trial
To investigate the safety and effectiveness of preoperative aerosol inhalation ICG solution for thoracoscopic accurate resection of congenital lung malformations in children.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
children with congenital lung malformations diagnosed by CT or MRI scan
Disqualifiers
1. ages <3 months and >14 years 2. complicated other life-threatening disease; 3. complicated severely pulmonary infection
Trial design
Single group
Treatments tested in this trial
atomized inhalation ICG before thoracoscope pneumonectomy
Procedure/SurgeryPreoperative preparation ICG solution dissolved in 5ml of normal saline (dose 0.5mg/kg) was inhaled 30 minutes before surgery. Operation method After entering the chest cavity, the fluorescence endoscope was switched to the fluorescence display mode, and the fluorescence-stained normal lung tissue and non-stained lesion tissue could be clearly displayed through the display screen, and the external boundary of the lesion was marked with an electric hook. The mediastinal pleura and pulmonary pleura were opened along the boundary of the lesion, and the lung tissue was split along the gap between the lesion and the lung tissue with an electric coagulation hook and an ultrasonic knife, and the lesion arteries and bronchi were freed.
Treatment groups
Trial outcomes
Primary outcomes
rate residual
Residual lesions can usually only be found in postoperative radiology scan
Secondary outcomes
peak volume ratio
Pulmonary function review ventilator-function indicators of peak volume ratio
length of hospital stay
length of hospital stay
peak time ratio
Pulmonary function review ventilator-function indicators of peak time ratio
Sponsors and contacts
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Jiexiong Feng
Lead sponsor
Tongji Hospital
Sponsor institution