About this trial
Septic shock is a critical condition associated with high mortality. Transthoracic echocardiography is widely used to evaluate cardiac function and guide treatment. Left and right atrial strain (LAS and RAS) measured via speckle tracking echocardiography have shown prognostic value in cardiovascular diseases. However, differences exist between echocardiographic software, leading to challenges in result comparability. This study aims to compare LAS and RAS measurements between ECHOPAC and UWS software, evaluate AutoStrain technology, and assess reproducibility across observers. The study is non-interventional and will use retrospective echocardiographic data from patients treated for septic shock. The findings will contribute to improving measurement standardization in critically ill patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age: >18 years
Adult patients admitted to critical care for septic shock (SEPSIS-3 definition)
TTE performed as part of medical management
No objection to data usage
Disqualifiers
Pregnancy
Moderate to severe valvular regurgitation/stenosis (>grade 2)
Ventricular or supraventricular tachyarrhythmia (HR >140 bpm) at the time of TTE
Poor echogenicity preventing LAS measurement
Trial population
Adult patients admitted to critical care for septic shock (SEPSIS-3 definition)
Trial design
Case-only
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
variation of LASr between ECOPAC and UWS
Agreement of LAS Reservoir Phase (LASr) measurement in manual mode between ECHOPAC and UWS
Secondary outcomes
variation of LAScd between ECHOPAC and UWS
Comparison of LAS Conduit (LAScd) measurements in manual mode between ECHOPAC and UWS
variation of LASct between ECHOPAC and UWS
Comparison of LAS Conduit (LAScd) and Contraction (LASct) measurements in manual mode between ECHOPAC and UWS
Comparison of LASr measurements in apical 2-chamber views
Comparison of LASr measurements in apical 2-chamber views in manual mode between ECHOPAC and UWS
Comparison of LAScd measurements in apical 2-chamber views
Comparison of LAScd measurements in apical 2-chamber views in manual mode between ECHOPAC and UWS
Sponsors and contacts
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Centre Hospitalier Universitaire, Amiens
Lead sponsor
Henri Mondor University Hospital
Collaborator