Attitudes Towards Deprescribing Medications in Cancer Patients and Impact of Educational Intervention by a Clinical Pharmacist

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIuliu Hatieganu University of Medicine and Pharmacy

About this trial

Participation in this study consists in responding to some questions from two questionnaires in Romanian about how participants feel about deprescribing, participants' treatment and how participants understand medical information. After that, participants will receive a brochure and watch a video with some basic information about medications and participants' involvement in treatment decisions and in the next visit for cancer treatment participants will be asked to answer questions from one of the initial questionnaire.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

cancer patients in palliative treatment

ECOG 1-2

Disqualifiers

cancer patients in curative treatment

ECOG 3-4

cognitive impairment

Trial design

Design model

Single group

Treatments tested in this trial

  • Educational intervention by a clinical pharmacist

    Other intervention

    All participants will respond to two questionnaires, both validated in Romanian and some demographic information. One is the rPATD questionnaire that investigate attitudes towards deprescribing of medication and the other one is the HLS-EU-Q16 that investigates medical literacy of participants. After completion, the clinical pharmacist will give a brochure and a video about the process of deprescribing, information about the efficacy and the adverse reactions of medicines and the role of pacient in treatment decision. When participants come to another cancer treatment (after 14 , 21 or 28 days), the rPATD will be completed again.

Treatment groups

120 Participants
are divided into 1 treatment group
Group A: Educational intervention by a clinical pharmacistExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Impact of educational intervention performed by clinical pharmacist

Participants will be asked to complete the same questionnaire before and after an educational intervention in order to assess if this kind of educational intervention is suitable for Romanian participants. Based on answers given to the same questions before and after the intervention, investigators can see if and what is changed in the perception of participants.

Time frame
from enrollment to the next cycle of oncological treatment (14, 21 or 28 days days)

Secondary outcomes

1

Attitudes towards deprescribing medications in cancer patients in palliative treatment

Using the rPATD questionnaire (revised Patients Attitudes Towards Deprescribing ), investigators assess if Romanian cancer patients are willing to have their medication deprescribed. The questionnaire has 4 factors: Burden, Appropriateness, Involvement and Concerns about Stopping. Each factor consists of 5 statements and participants are invited to respond to a 5-point Likert scale (strongly agree =5, agree =4, unsure =3, disagree =2, strongly disagree =1). Factors' scores are calculated as the average of the summed score for the five statements pertaining to each factor, with a final score per factor ranging from 1 to 5. A higher score indicates a greater perceived burden, higher concerns about stopping and greater involvement in medication related decisions. The appropriateness factor is reversed scored so that a higher score indicates a greater belief in the appropriateness of current medications

Time frame
from enrollment to the next cycle of oncological treatment (14, 21 or 28 days days) when they answer the second time
2

The level of health literacy

Using the questionnaire HLS-EU-Q16 investigators can asses the level of health literacy of participants. Each of the 16 items are scored on a 4-point Likert scale ranging from 1 ("very difficult") to 4 ("very easy"). For interpretation of the final score, all items of the scale are summed, giving a score ranging between 0 (no health literacy) to 16 (high health literacy). For ease of interpretability, the three levels are identified: inadequate health literacy (0-8), problematic health literacy \[9-12\], and sufficient health literacy

Time frame
at enrollment

Other outcomes

1

Demographic characteristics of the population included in this study

Investigators will be able to characterize a population of cancer patients in Romania: number of medications, number of diseases, social background (still working or retiered) , literacy (under 8 classes, 8 classes, highschool, vocational school, superior degree).

Time frame
at enrollment

Sponsors and contacts

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