Musculoskeletal disorders are an heterogeneous group of diseases that represent one of the major causes of disability. Considering the importance of studying these pathologies, it is necessary to develop research lines based on the availability of human biological material from highly clinically relevant patients. The purpose of this project is therefore the establishment of a bank of biological material (biobank) to investigate important aspects related to the pathologies of the musculoskeletal system through subsequent bio-molecular characterization studies.
Patients admitted to our Institute
Patients aged ≥18 years
Patients with osteoarthritis of hip or knee and rehabilitated in the institute
Patients with primary and secondary tumors of the skeleton
Participants aged <18 years
Participants unable to release the Informed Consent
The target group corresponds to the patients admitted to our Institute who are candidates for the following surgical or biopsy procedures: * patients with osteoarthritis of the hip or knee and rehabilitated in the institute * patients with primary and secondary tumors of the skeleton * patients undergoing prosthetic examination as a result of plant infection The population will include adult subjects. Patients will be considered eligible for enrollment in the project if they can provide informed written consent.
Cohort
Prospective
collection of waste materials
Other interventionosteoarthritis of the hip or knee and rehabilitated in the institute; primary and secondary tumors of the skeleton; prosthetic examination as a result of plant infection
BioBanking of waste biological materials
The aim of the project is to create a biobanch of waste material from patients undergoing prosthetic surgery and hospital rehabilitation and oncologic orthopedic surgery to be used in specific studies aimed at defining the pathophysiological bases and / or new possible criteria Diagnostic / prognosis of locomotor system pathologies and, specifically, osteoarthritis of the hip and knee, primary and secondary bone tumors, infection of hip and knee prostheses requiring plant revision.
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