Basic and Clinical Research of Pregnancy-Induced Hypertension

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age20-50
SponsorSecond Affiliated Hospital of Wenzhou Medical University

About this trial

Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Heart disease, infections, etc. in pregnant women Uncooperative patients

Trial population

Healthy parturient women, women who have had miscarriages, patients with pregnancy-induced hypertension

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • no Intervention

    Other intervention

    observation

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: control group1 intervention
Group B: PIH group1 intervention

Trial outcomes

Primary outcomes

1

PIH

the content of GPR18 type macrophages

Time frame
Early pregnancy:Weeks 1 to 12 (the first to third months of pregnancy) ;mid-pregnancy:Weeks 13 to 27 (the 4th to 6th month of pregnancy) ;post-delivery period:Weeks 28 to 40 (the 7th to 9th months of pregnancy);the day of delivery。

Secondary outcomes

1

PIH

Blood pressure

Time frame
delivery
2

PIH

SPM content

Time frame
delivery
3

PIH

Spiral artery morphology

Time frame
delivery

Other outcomes

Sponsors and contacts

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