The goal of this clinical research study is to learn more about whether individual differences in brain responses to emotional triggers impact rTMS (repetitive transcranial magnetic stimulation) responses in people who smoke.
Age 21 to 60 years
Report smoking on average, 5 or more cigarettes, little cigars and/or cigarillos per day, within the past 30 days preceding the screening visit.
Expired carbon monoxide (CO) ≥ 6ppm and/or test positive for cotinine using a urine cotinine test on day of study visit.
Able to follow verbal and written instructions in English and complete all aspects of the study.
rTMS exposure for treatment or research purposes in the last 6 months.
History of seizure, epilepsy, syncope, fainting episode, or head trauma resulting in loss of consciousness.
Presence or history of neurological disorders (migraine, stroke, Alzheimer's Disease and other Dementias, Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury (TBI), increased intracranial pressure).
History of brain surgery, implanted electronic device, metal in the head.
Single group
Repetitive Transcranial Magnetic Stimulation (rTMS)
Procedure/SurgeryTMS is a non-invasive procedure in which a coil is placed over the scalp, and focused magnetic pulses are applied to parts of the brain through the coil.
Safety and Adverse Events (AEs)
Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0
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