About this trial
Evaluation of progressive pregnancy rates (with an embryo with cardiac activity at 12 weeks), on a first attempt at IVF/ICSI (fresh and frozen embryo transfers) following the discovery of one or two endometrioma(s) of 30 to 80 mm, without a history of cystectomy, and comparison between the two groups: ethanol sclerotherapy and therapeutic abstention
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Infertile women aged 18 to 43,
Presenting one or 2 endometriotic cysts of 30 mm to 80 mm long axis, confirmed by ultrasound and/or pelvic MRI and without signs of atypia,
With indication of IVF/ICSI, first IVF/ICSI after the discovery of endometriosis cyst(s),
Having given their consent.
Disqualifiers
A history of ovarian cystectomy,
A non-homogeneous cyst that cannot be punctured (risk of incomplete aspiration),
Complex adnexal image that cannot exclude an associated hematosalpinx (communicating hematosalpinx, tissue component),
A recent tubo-ovarian infection,
Trial design
Parallel
Treatments tested in this trial
ethanol sclerotherapy
Procedure/SurgeryThe originality of this project consists in evaluating the effectiveness of ethanol sclerotherapy of endometrioma(s) in infertile patients before IVF/ICSI, excluding patients who have previously had an ovarian cystectomy. To date, no prospective randomized comparative study between ethanol sclerotherapy of endometriomas and therapeutic abstention has been carried out.
Treatment groups
Trial outcomes
Primary outcomes
cumulative rate of active pregnancies
Cumulative rate of active pregnancies defined by the presence of an embryo with cardiac activity at 12 weeks per IVF/ICSI cycle, including fresh and frozen embryo transfers in an IVF/ICSI attempt.
Locations
Sponsors and contacts
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