About this trial
The objective of the study is to evaluate the functional benefit of left bundle branch of His pacing compared to right ventricular pacing in patients implanted with a pacemaker prior to a atrioventricular node ablation procedure for rapid atrial fibrillation
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Impairment of autonomy such that a maximal cardiorespiratory effort test (VO2 Max test) cannot be performed under good conditions (ADL scale < 5).
LVEF < 40% at inclusion
Person deprived of liberty by an administrative or judicial decision, or person under court protection, sub-guardianship or curatorship.
Patient participating in another interventional trial
Trial design
Crossover
Treatments tested in this trial
left bundle branch of His pacing
Procedure/Surgeryleft bundle branch of His pacing
right ventricular pacing
Procedure/Surgeryright ventricular pacing
Treatment groups
Trial outcomes
Primary outcomes
Maximum Oxygen Consumption (VO2 max) in mL/min/kg.
Secondary outcomes
walking test distance covered
echography criteria: LVEF (%), indexed left ventricular end-systolic volume (mL/m2), indexed cardiac output (L/min/m2), inter-ventricular asynchrony criteria (aortic pre-ejection time - pulmonary pre-ejection time)
Determination of NT pro BNP or BNP
Physical component of quality-of-life scale (SF-36)
Sponsors and contacts
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