The objective of the study is to improving the results of surgical treatment of liver echinococcosis complicated by biliary fistula by optimizing diagnostic approaches to early verification of this complication and improving the tactical and technical aspects of its elimination.
Age under 18 years;
Informed consent for inclusion in the study;
The presence of liver echinococcosis, for which conservative surgical treatment will be performed;
The presence of the entire spectrum of necessary preoperative diagnostic measures;
Age under 18 years;
Refusal to participate in the study;
Extrahepatic echinococcosis without liver damage;
Absence of the full range of preoperative diagnostic data;
Single group
Conservative surgical treatment of liver echinococcosis, verification of occult biliary fistulas and their elimination by weaving and using medical cyanoacrylate glue
Procedure/SurgeryIn conservative surgical operations for liver echinococcosis, the biliary fistula is identified, onto which a U-shaped suture is applied, after which medical cyanoacrylate glue is applied between the suture stitches to the fibrous capsule in the fistula area and the suture threads are tied.
Measuring the incidence of bile leakage after conservative surgical interventions for liver echinococcosis
assessing the effectiveness of the method for eliminating biliary fistulas in the fibrous capsule during organ-preserving surgeries for liver echinococcosis, characterized by creating a two-level strengthening of the fistula area by applying U-shaped sutures and a cyanoacrylate adhesive composition
Measuring the time of closure of biliary fistulas in the postoperative period
In the group of patients with the development of biliary fistulas after surgery, the time of their closure in days will be studied
Measuring the costs of treating patients with liver echinococcosis
Economic costs will be assessed for patients with liver echinococcosis who undergo conservative surgical interventions, taking into account the absence or development of bile leakage in the postoperative period
Measurement of the quality of life of patients after conservative surgical interventions for liver echinococcosis.
The quality of life will be analyzed using the SF-36 (The 36-Item Short Form Survey) questionnaire in patients after conservative surgical interventions, taking into account the absence or development of bile leakage in the postoperative period. It stems from a study called the Medical Outcomes Study for the objective measure of the quality of life. Scores for the various domains are transformed and combined using a scoring key to obtain a total score indicating a range from low to high quality of life (from 0 to 100 points). Scores for two components, the physical component and the mental component, can also be calculated.
Click on the lead sponsor to view all of their trials.