About this trial
The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation.
The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke.
The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patient over 18 years old
Patient with a cerebral AVM for which an intervention (endovascular treatment or surgery) or only clinical monitoring
Express consent to participate in the study
children
Disqualifiers
Patient benefiting from a legal protection measure
Pregnant or breast feeding woman
Trial population
Patient with a cerebral arterioveinus malformation for which an intervention (endovascular treatment or surgery) or only clinical monitoring is planned
Trial design
Case-only
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Associaton between dosage of endothelial marker and the arteriovenous malformation pronostic
associaton between dosage of endothelial marker in blood samples and correlation with clinical outcome
Associaton between dosage of platelet and the arteriovenous malformation pronostic
Dosage of platelet in blood samples and correlation with clinical outcome
Associaton between dosage of neutrophilic and the arteriovenous malformation pronostic
Dosage of neutrophilic in blood samples and correlation with clinical outcome
Associaton between neo-angiogenesis activation markers and the arteriovenous malformation pronostic
Dosage neo-angiogenesis activation markers in blood samples and correlation with clinical outcome
Sponsors and contacts
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