Biomarkers and Unstable Carotid Plaque
ConditionCarotid Artery Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS
About this trial
This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy.
Age>18 years
Disqualifiers
Presence of significant internal carotid artery stenosis referred to carotid artery stenting
Trial population
All the patients with significant internal carotid artery stenosis referred to the Unit of Vascular Surgery of Fondazione Policlinico Gemelli IRCCS Rome for carotid artery endoarterectomy.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Carotid endarterectomy
Procedure/SurgeryCarotid endarterectomy, plaque histological analysis and miRNA expression
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
miRNA levels
miRNA levels and plaque vulnerability
Time frame
30 daysSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov