Acupuncture points or acupoints are fundamental to the practice of acupuncture, yet their scientific basis remains unclear. According to traditional explanations of acupuncture, acupoints can become tender or more sensitive to pressure when there is an underlying disease of the body. Findings from recent basic animal studies support this traditional theory. For example, compared to healthy control animals, models of colitis have shown increased skin temperature, blood flow, and pain sensitivity at specific body regions that correspond to the location of acupoints that are commonly used in acupuncture treatment for colitis. However, little is known about whether these findings apply to humans.
adults (age 18 years or older)
clinical diagnosis of ulcerative colitis or Crohn's disease
any history of serious musculoskeletal or soft tissue injury of the lower and/or upper extremities
presence of scarring or tattoo on the lower and/or upper extremities
presence of serious cardiac diseases, severe dermatological conditions, peripheral neuropathy, infectious disease, psychological illnesses, or other serious co-morbidities (e.g., cancer)
prior history of colostomy or ileostomy
Adults with inflammatory bowel disease (IBD) and healthy control participants will be enrolled into the study from the Greater Boston area.
Other
Cross-sectional
Not listed
Skin blood perfusion
Comparisons of cutaneous blood perfusion at predefined regions or points of interest between IBD patients and healthy control participants, as measured by laser speckle contrast imaging (LSCI). LSCI is a non-invasive imaging technique for assessing superficial tissue blood perfusion.
Skin temperature
Comparisons of skin temperature at predefined regions or points of interest between IBD patients and healthy control participants, as measured by infrared thermography.
Pressure pain threshold
Comparisons of pressure pain threshold (PPT) at predefined points of interest between IBD patients and healthy control participants, as measured by pressure algometry.
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Brigham and Women's Hospital
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
Collaborator
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