BLOCK-TRAUMA Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-50
SponsorUkrainian Society of Regional Anesthesia and Pain Therapy

About this trial

This prospective cohort study will evaluate the association between the overall burden of regional anesthesia and early clinical outcomes in adult patients with polytrauma.

Patients with severe trauma often experience pain from multiple injury sites and may require more than one peripheral nerve block or continuous regional anesthesia catheter. While regional anesthesia can improve pain control and reduce opioid use, multiple blocks and catheters may also increase treatment complexity, local anesthetic exposure, motor weakness, and monitoring challenges.

The study will prospectively collect data on the number and type of regional anesthesia procedures, local anesthetic exposure, catheter use, pain intensity, opioid consumption, mobility, complications, and early recovery outcomes. The goal is to determine whether increasing regional anesthesia burden is associated with improved analgesia, functional recovery, or increased risk in polytrauma patients.

Eligibility criteria

Qualifiers

Adults aged 18 years or older.

Diagnosis of polytrauma, defined as traumatic injuries involving two or more anatomical regions.

Injury Severity Score (ISS) ≥16.

Hospital admission within 48 hours after injury.

Disqualifiers

Age younger than 18 years.

Isolated single-system injury without polytrauma. ISS <16.

Expected survival less than 24 hours after admission.

Severe traumatic brain injury or impaired consciousness preventing reliable pain and functional assessment, unless validated behavioral pain scales can be used.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

500 Participants
are grouped into 1 trial group