Blood Flow Restriction Training for People With Disabilities
ConditionWeakness, Muscle
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical College of Wisconsin
About this trial
A large portion of the American population live with disabilities. People with disabilities can find it difficult to perform standard exercise routines. Regular exercise is necessary to be healthy, especially as people age. Lack of exercise can lead to secondary health concerns, like loss of muscle mass, diabetes, heart attack or stroke, to name a few. For exercise to be most beneficial, a certain degree of intensity must be achieved. Low load blood flow restriction training may be able to mimic the intensity of beneficial exercise without actually exercising hard. It may be a good option for people with disabilities who find it difficult to exercise.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Male or female
Age > or = 18
English speaking
Able to understand and perform upper extremity exercises
Disqualifiers
Pregnant
Body mass index >40 kg·m-2
Uncontrolled hypertension (>150/90 mmHg)
Presence of neuromuscular junction and other muscle diseases
Trial design
Design model
Parallel
Treatments tested in this trial
Blood flow restriction training
Other interventionParticipants randomized to blood flow restriction training will complete low load resistance training exercises while the limb is occluded at 80% arterial occlusion pressure.
No blood flow restriction training
Other interventionParticipants randomized to no blood flow restriction training will complete low load resistance without occlusion.
Treatment groups
24 Participants
are divided into 2 treatment groupsGroup A: Low load resistance training with blood flow restrictionExperimental treatment 1 intervention
Group B: Low load resistance trainingActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Difference in strength between low load blood flow restriction resistance training and low load resistance training
This outcome will measure the efficacy of low load blood flow restriction training (LLBFR) on muscle strength. The difference in muscle strength as measured by change in 1-repetition maximum weight in pounds will be compared in individuals training with LLBFR on their arm extensors and individuals training with low load resistance training (LLRT) on their arm extensors compared to their baseline.
Time frame
6 weeks2
Difference in arm circumference between low load blood flow restriction resistance training and low load resistance training
This outcome will measure the efficacy of low load blood flow restriction training (LLBFR) on arm circumference. The difference in arm circumference as measured by tape measure will be the change in centimeters in individuals training with LLBFR on their arm extensors compared to individuals training with low load resistance training (LLRT) on their arm extensors when compared to their respective baseline.
Time frame
6 weeks3
Difference in muscle thickness change between low load blood flow restriction resistance training and low load resistance training
This outcome will measure the efficacy of low load blood flow restriction training (LLBFR) on muscle thickness. The difference in muscle thickness as measured by ultrasound will be the change in centimeters in individuals training with LLBFR on their arm extensors compared to individuals training with low load resistance training (LLRT) on their arm extensors when compared to their respective baseline.
Time frame
6 weeksSecondary outcomes
1
The interaction effect between disability status (disable versus able-bodied) and training group (LLBFR and LLRT) on the change in strength.
Response to training in individuals with disabilities. The results of LLBFR on muscle strength as measured by change in pounds of 1-repetition maximum to the arm extensors will be compared between those with disabilities and those without.
Time frame
6 weeks2
The interaction effect between disability status (disable versus able-bodied) and training group (LLBFR and LLRT) on the change in arm circumference.
Response to training in individuals with disabilities. The results of LLBFR on arm circumference as measured by change in centimeters as measured by tape measure to the arm extensors will be compared between those with disabilities and those without.
Time frame
6 weeks3
The interaction effect between disability status (disable versus able-bodied) and training group (LLBFR and LLRT) on the change in muscle thickness.
Response to training in individuals with disabilities. The results of LLBFR on muscle thickness as measured by ultrasound in change in centimeters to the muscle thickness will be compared between those with disabilities and those without.
Time frame
6 weeksSponsors and contacts
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Source ClinicalTrials.gov