Body Donation in HHT
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Essen
About this trial
The possibility of body donation in hereditary hemorrhagic telangiectasia (HHT) means that human tissue samples with and without vascular malformations can be analyzed. The aim is to gain insights into the disease mechanism.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
positiv genetic testing for HHT and/ or at least three fulfilled Curacao Criteria
older than 18 years
Disqualifiers
missing inclusion criteria
Trial design
Design model
Single group
Treatments tested in this trial
body donation in HHT
Other interventionBody donation in HHT
Treatment groups
5 Participants
are divided into 1 treatment groupGroup A: HHT PatientsOther 1 intervention
Trial outcomes
Primary outcomes
1
Differences in immune and endothelial cells in tissue with and without telangiectasia in HHT
Analysis of the differences in tissue with and without telangiectasia in HHT, e.g. immunfluorescence staining of tissue / bone with endoglin-/ alk 1- antibodies and quantitative analysis of endoglin/ alk1 lacking cells such as immune cells or endothelial cells
Time frame
after the patients who gave informed consent died their body will be donated to the Institute of Anatomy of the University Hospital Essen, samples will be taken until the body is cremated (regularly within 12 months)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
University Hospital, Essen
Lead sponsor
University Hospital Marburg
Collaborator
Johannes Gutenberg University Mainz
Collaborator
Source ClinicalTrials.gov