Boron Levels, Oxidative Stress, and Inflammation in Periodontitis

ConditionPeriodontitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorMarmara University

About this trial

This cross-sectional observational study aims to evaluate the relationship between boron levels and oxidative stress, antioxidant defense, and inflammatory markers in individuals with periodontitis. The study will include systemically healthy, non-smoking individuals divided into two groups: periodontally healthy controls and patients with Stage III-IV periodontitis. Boron levels and selected oxidative stress, antioxidant, and inflammatory biomarkers will be evaluated in saliva and gingival tissue samples. The findings will be compared between the groups to investigate the potential relationship between boron levels and periodontal inflammation and oxidative stress.

Eligibility criteria

Qualifiers

Volunteering to participate in the study and signing the informed consent form

Being between 18 and 65 years of age

Being systemically healthy

No antibiotic use within the last 3 months

Disqualifiers

Incomplete or unreliable clinical measurements

Insufficient saliva or gingival tissue sample for biochemical analyses

Regular use of boron-containing oral care products within the last 3 months

Regular consumption of boron-rich supplements or mineral waters

Trial design

Treatments tested in this trial

  • Biochemical Assessment of Saliva and Gingival Tissue

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators