Brain Activity During Bladder Filling: Pilot Study of an fMRI Protocol
ConditionfMRI Research
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-35
SponsorUniversity Hospital, Ghent
About this trial
Urinary incontinence is the most frequently observed lower urinary tract symptom (LUTS) in children with cerebral palsy (CP) (Samijn et al., 2016).
Higher brain centers responsible for bladder function may be related to the presence of incontinence.
The current pilot study is the first study of a research project focusing on correlations between brain damage and incontinence.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Healthy adults
Disqualifiers
lower or upper urinary tract dysfunction
Trial design
Design model
Single group
Treatments tested in this trial
invasive urodynamic evaluation
Diagnostic testInvasive urodynamic evaluation to define maximum cystometric capacity. By means of catheterisation the bladder gets filled and volumes en pressures are measured.
functional magnetic resonance imaging during bladder filling
Diagnostic testFunctional MRI is used to capture brain activity during tasks. The task in the current study is bladder infusion and withdrawal by means of the INFSYS-2 infusion/withdrawal pump (Leitner et al. 2017)
Treatment groups
6 Participants
are divided into 1 treatment groupGroup A: Complete evaluation UDO and fMRIExperimental treatment 2 interventions
Trial outcomes
Primary outcomes
1
Activated brain regions demonstrating brain activity
fMRI brain imaging data will be analyzed using FMRIB Software Library v6.0 (FSL).
Time frame
through study completion, an average of 6 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: