About this trial
This is a controlled study of patients with and without primary premature ejaculation. It is based on near-infrared spectroscopy (NIRS) functional brain imaging to detect and compare changes in brain activity in resting and task states (Simulated Sex) between the two groups of patients.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
patients' age varied from 18 to 45 years;
patients met the 2014 International Society for Sexual Medicine (ISSM) definition criteria for PPE;
patients had a stable, heterosexual relationship with a single sexually active female partner for at least 6 months and with at least two sexual intercourses a week and kept stable during the study period;
Patients with premature ejaculation lasting longer than 6 months;
Disqualifiers
patients were diagnosed with secondary PE, variable PE, and subjective PE;
patients were using medications for endocrinological, metabolic, chronic systemic, or psychiatric diseases;
patients were abusing alcohol or illegal drugs;
patients were diagnosed with erectile dysfunction (ED) if their scores were <21 on the abridged five-item International Index of Erectile Function (IIEF-5)
Trial design
Parallel
Treatments tested in this trial
Detecting Brain Activity with Functional Near Infrared Spectroscopy
Diagnostic testUse a functional near-infrared spectroscopy to detect brain activity in the two groups of subjects during resting state and task state.
Treatment groups
Trial outcomes
Primary outcomes
Results of near-infrared brain functional imaging
Data on changes in oxygenated hemoglobin concentration
Sponsors and contacts
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