Cervical spinal cord stimulation can elicit arm and hand movements through recruitment of proprioceptive neurons in the dorsal roots. In participants with cervical spinal cord injury, the spare roots bellow the lesion can be used to reactivate motor function. Decoding of motor intentions can be achieved through implantable electrocorticography (ECoG) devices.
In this study, the investigators will use an investigational system using ECoG signal recording over the motor cortex to drive muscle specific electrical epidural spinal cord stimulation (EES). The investigators will assess the safety and preliminary efficacy of this system in 3 participants.
Must provide Informed Consent as documented by signature (Appendix Informed Consent Form),
Must be at least 18 years old and no older than 75 years old at the time of enrolment,
Must be suffering from non-progressive traumatic cervical spinal cord injury,
Must be graded A, B, C, or D in the American Spinal Injury Association (ASIA) Impairment Scale (AIS) classification,
None
Single group
ARC-BSI Cervical system
DeviceUnilateral implantation of a 64 channel - ECoG array over the sensory motor cortex combined with an implantation of 32 channel spinal cord stimulation system over the cervical region. The system decodes the motor attempts of the participant and translates those intentions into modulation of electrical stimulation.
Number of treatment-related serious adverse events (SAEs).
Graded and Redefined Assessment of Strength Sensibility, and Prehension (GRASSP) score
0-232 points, higher score indicating better performance
Action Research Arm Test (ARAT) score
0-57 points, higher score indicating better performance
Capabilities of the Upper Extremity Test (CUE-T)
0-68 points, higher score indicating better performance
Range of Motion (in rad)
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