Brain Imaging in Babies Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-75
SponsorKing's College London

About this trial

The aims of the BIBS Study

The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age. Working with children from a variety of backgrounds and communities, the investigators use a combination of state-of-the-art diagnostic tools such as MRI scans alongside traditional behavioural assessments to capture the earliest information on infant brain development.

The focus of the BIBS study

MRI scanning is a safe way of producing detailed images using strong magnetic fields and radio waves. It does not use X-ray. Along with learning more about brain development in general, the investigators also try to identify features that may in future help predict whether a child will or will not develop traits of conditions such as Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD). Long-term, this may help target useful interventions early on, helping children who are most in need.

Since COVID-19 arrived in the United Kingdom (U.K.) in 2020, the investigators have been given ethical approval to include testing for this infection in the mothers and children participating in the study. This may provide an opportunity to better understand how mother and baby respond to infections. The investigators particularly welcome mothers who have had a positive COVID-19 test during their pregnancy to join the study.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Pregnant mothers with and without confirmed COVID-19

Infants with and without an immediate family history of Autism Spectrum and neurodevelopmental conditions

Based in England, UK

Disqualifiers

based on further screening

Trial population

Community Sample

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

790 Participants
are grouped into 2 trial groups
Group A: Infants a family history of ASD/ADHD
Group B: Infants without a family history of ASD/ADHD

Trial outcomes

Primary outcomes

1

Neurodevelopmental Outcomes

Time frame
3-4 years of age

Secondary outcomes

Other outcomes

Sponsors and contacts

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