Breathing Patterns in Infants Before and After Extubation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-6
SponsorChristiana Care Health Services
About this trial
The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spontaneous breathing tests (SBTs) in intubated premature infants admitted to the ChristianaCare NICU.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
premature infants (born at ≤32 weeks gestation) who are intubated.
medical team is evaluating the baby for extubation readiness
Disqualifiers
Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of RIP measurements will be excluded.
Trial population
The study population includes premature infants, admitted to the NICU at Christiana care and who are intubated.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Observation
Other interventionInfants work of breathing will be observed through placement of soft elastic cloth bands on the infant's chest and abdomen. These bands measure how well the chest and abdomen work together when a baby breathes.
Treatment groups
30 Participants
are divided into 1 treatment groupGroup A: Preterm infants who are intubated1 intervention
Trial outcomes
Primary outcomes
1
Work of breathing before and after extubation
The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. We will observe work of breathing for 5-10 minutes before the infant is extubated and 5-10 minutes after the infant is extubated.
Time frame
25 minutesSecondary outcomes
1
Ability of work of breathing indices to predict extubation failure.
The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spontaneous breathing tests (SBTs) in intubated premature infants admitted to the ChristianaCare NICU. We will record a baby's work of breathing measurements for 5-10 minutes before the routine spontaneous breathing test, up to 5 minutes during the spontaneous breathing test, and for 5-10 minutes after the spontaneous breathing test.
Time frame
25 minutesSponsors and contacts
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Source ClinicalTrials.gov