BRIDGE-SIC Efficacy Trial
ConditionCancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDana-Farber Cancer Institute
About this trial
This is a pragmatic, prospective, randomized clinical trial to test the effectiveness of large language model (LLM)-generated serious illness conversation (SIC) summaries delivered to patients' inpatient and outpatient clinicians at the time of hospital admission on the primary outcome of days in the hospital in the next 90 days.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
DFCI Patients, defined as patients who have a DFCI medical record number.
Admitted to an inpatient solid tumor medical oncology service at BWH (including beds that are considered to be DFCI beds within BWH)
Age ≥ 18 years
Mortality prediction ≥ 25%
Disqualifiers
None
Trial design
Design model
Single group
Treatments tested in this trial
LLM-generated SIC summary email to clinical teams
BehavioralAn email containing a summary of prior serious illness conversations, generated by a large language model, is sent to the patient's clinical teams at admission, prompting review and discussion of care preferences.
Treatment groups
600 Participants
are divided into 2 treatment groupsGroup A: Arm 1: Intervention ArmExperimental treatment 1 intervention
Group B: Arm 2: Control ArmNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Number of Days in the Hospital
The number of days in the hospital is defined as the total number of inpatient days, including days from the index hospitalization and any subsequent hospital admissions during the follow-up period.
Time frame
90 days after randomizationSecondary outcomes
1
Number of Hospital Readmissions
The number of hospital readmissions is defined as the total number of inpatient hospital readmissions, excluding the index hospitalization.
Time frame
90 days after randomizationSponsors and contacts
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Source ClinicalTrials.gov