Bronchial Response to Exercise After Double Lung Transplantation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20+
SponsorChang Gung Memorial Hospital
About this trial
This study aims to investigate the airway response to exercise and its association with breathlessness in double lung transplant recipients by comparing responses during 5-minute and 15-minute exercise durations.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Received double lung transplantation
≥ 3 months post-transplant
Disqualifiers
Diagnosis of asthma
Significant airflow limitation (≤50% FEV1 predicted)
Inability to cooperate with the required tests and measurements
Recent infection or rejection within 1 month
Trial population
double lung transplantation recipients
Trial design
Design model
Case-only
Time perspective
Prospective
Treatments tested in this trial
Exercise
Other intervention5 minutes of constant workload exercise at 60% of peak oxygen uptake from cardiopulmonary exercise testing
Exercise
Other intervention15 minutes of constant workload exercise at 60% of peak oxygen uptake from cardiopulmonary exercise testing
Treatment groups
40 Participants
are divided into 1 treatment groupGroup A: double lung transplant recipients1 intervention
Trial outcomes
Primary outcomes
1
Percentage change in FEV1 from baseline
Percentage change in FEV1 from baseline at immediately post-exercise, 5, 10, 15, 20, and 30 minutes post-exercise.
Time frame
from enrollment to up to 12 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Chang Gung Memorial Hospital
Lead sponsor
National Taiwan University
Collaborator
Source ClinicalTrials.gov