Bronchoscopic Versus Airway Exchange Catheter-Guided Endotracheal Tube Exchange

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorLéo Franchetti

About this trial

This prospective experimental study compares two methods for replacing an endotracheal tube in Thiel-embalmed body donors. The conventional method uses an airway exchange catheter based on the Seldinger technique, whereas the investigational method uses a flexible bronchoscope to provide direct visual guidance throughout the exchange.

The primary outcome is the duration of interrupted ventilation, measured from cessation of ventilation until ventilation is resumed through a correctly positioned replacement tube. Secondary outcomes include unsuccessful tube exchange requiring complete reintubation, duration of individual procedural steps, procedures lasting more than 60 seconds, use of additional rescue equipment, and unforeseen technical difficulties.

Both techniques will be performed in two Thiel-embalmed donated human bodies using an alternating sequence. Four experienced physicians will perform 40 tube exchanges per technique, resulting in a total of 80 procedures.

Eligibility criteria

Qualifiers

Human body donor preserved using the Thiel embalming method.

Intact trachea without relevant postmortem or preparation-related lesions.

Documented consent for scientific use of the body and confirmation of anatomical suitability by the Institute of Anatomy.

Sufficient mobility of the neck, jaw, and laryngeal region to permit realistic tube-exchange maneuvers.

Disqualifiers

Tumor or stenosis involving the larynx, trachea, or central airways.

Previous surgery or radiotherapy involving the larynx or oral cavity.

Previous pneumonectomy.

Previous tracheotomy or laryngectomy.

Trial design

Treatments tested in this trial

  • Airway Exchange Catheter-Guided Endotracheal Tube Exchange
  • Bronchoscope-Guided Endotracheal Tube Exchange

Treatment groups

2 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Léo Franchetti

Lead sponsor

University Hospital, Basel, Switzerland

Sponsor institution

University Hospital, Basel, Switzerland

Collaborator