Building Rapid Inpatient Delivery of ART to Generate Engagement in HIV Care
ConditionHIV Treatment
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Chicago
About this trial
The study team will pilot rapid antiretroviral therapy (ART) initiation as part of routine inpatient care at the University of Chicago Medicine (UCM), comparing outcomes over a 12-month implementation period. Electronic medical record (EMR) data will be used to evaluate clinical outcomes such as ART initiation within 24-48 hours, linkage to HIV care, retention, and viral suppression, as well as demographic and clinical factors associated with these outcomes. Implementation outcomes will be assessed using Proctor's framework, including acceptability, feasibility, fidelity, and appropriateness.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18 years of age or older
Admitted to the UCM General Medicine or Hospital Medicine wards during the study time period
Living with HIV
HIV viral load > 200 copies/mL
Disqualifiers
Less than 18 years of age
Not admitted to the UCM General Medicine or Hospital Medicine wards during the study time period
Not living with HIV
HIV viral load < 200 copies/mL
Trial population
University of Chicago Medicine adult inpatients living with HIV with elevated viral load
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Proportion of eligible inpatients with HIV who are started on ART within 24-48 hours of qualifying hospitalization
Rate of rapid ART initiation, as measured by the percentage of eligible inpatients with HIV who are started on ART within 24-48 hours of qualifying hospitalization
Time frame
Baseline to month 12Secondary outcomes
1
Time from admission to ART initiation
Outcome Measure: Time from admission to ART initiation, as measured by the average time in hours from time of admission to time of first ART dose administration among hospitalized inpatients with HIV
Time frame
Baseline to month 122
Rates of successful linkage to post-discharge HIV care
Rate of linkage to post-discharge HIV care, as measured by the percentage of PWH who attend at least 1 medical visit during the implementation phase (i.e., 1 year after hospitalization)
Time frame
Baseline to month 123
Short-term retention in care
Rate of retention in care, as measured by the percentage of PWH who attend at least two medical visits during the implementation phase (i.e., 1 year after hospitalization)
Time frame
Baseline through 12 months4
HIV viral suppression rates
Rate of HIV viral suppression, as measured by the percentage of PWH who achieve a viral load less than 200 c/mL at the end of the implementation phase (i.e., within 1 year after hospitalization)
Time frame
Baseline to month 12Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: