Butorphanol for Pain Relief After Cesarean Section: A Retrospective Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-55
SponsorSichuan Provincial People's Hospital

About this trial

This study explored the association between postoperative functional recovery and the formula of analgesic pumps as well as other related factors (such as age, intraoperative blood loss, operation duration, etc.) by retrospectively analyzing the clinical data of patients undergoing cesarean section in the main campus and branches of Sichuan Provincial People's Hospital from September 2024 to June 2025. The value of this study lies in: 1) providing a basis for optimizing the postoperative analgesia plan after cesarean section. 2) To provide references for the formulation of personalized analgesia strategies in clinical practice, improve the postoperative recovery quality of patients, promote the concept of enhanced recovery after surgery, and reduce the medical burden.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18-55 years

ASAI-III level

Scheduled or emergency cesarean section

Postoperative use of analgesic pump (formulation includes buprenorphine or tramadol or hydromorphone, etc.)

Disqualifiers

Postoperative analgesia pump usage time is less than 24 hours

Missing key information such as follow-up status in medical records

Trial population

Women who have given birth by cesarean section

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • An postoperative analgesic pump was used

    Drug

    The drugs in the analgesic pump include butorphanol, hydromorphone, tramadol, and other medications.

Treatment groups

2,500 Participants
are divided into 1 treatment group
Group A: The group using the analgesic pump1 intervention

Trial outcomes

Primary outcomes

1

Pain Score

The Visual Analog Scale (VAS) is primarily used, where 1 represents no pain (best outcome) and 10 represents the worst pain (worst outcome); other scales may be used if necessary.

Time frame
2 days post-surgery
2

Postoperative functional recovery status

Postoperative functional recovery status mainly includes: the time of first passage of gas, the time of first ambulation, the time of first catheter removal, and the recovery of limb muscle strength. The passage of gas, ambulation, and catheter removal times are self-reported by the patients, recording the days after surgery when the events occurred. The recovery of limb muscle strength is classified into six levels, ranging from 0 to 5, where 0 indicates no detectable muscle contraction (worst outcome) and 5 indicates normal muscle strength (best outcome).

Time frame
2 days post-surgery
3

Sedation score

The sedation score uses a scale from -5 to +4, where -5 is defined as coma (one of the worst outcomes); -4 is defined as severe sedation (responds to physical stimulation); -3 is moderate sedation (no response to auditory stimulation); -2 is mild sedation (unable to maintain alertness for more than 10 seconds); -1 is drowsiness (not fully awake but can stay awake for more than 10 seconds); 0 is the awake natural state (best outcome); +1 is restlessness and anxiety (anxious and tense, but only slight body movement); +2 is agitation and anxiety (intense body movement); +3 is very agitated (trying to remove body tubes); +4 is aggressive (violent behavior) (one of the worst outcomes).

Time frame
2 days post-surgery

Secondary outcomes

1

Overall patient satisfaction rating

Patient overall satisfaction is self-reported, with a score range from 0 to 100, where 0 represents the least satisfied (worst outcome) and 100 represents the most satisfied (best outcome).

Time frame
2 days post-surgery
2

Nausea and vomiting

Self-reported by the patient, with '1' indicating occurrence (worst outcome) and '0' indicating non-occurrence (best outcome).

Time frame
2 days post-surgery
3

Adverse reactions

Time frame
2 days post-surgery

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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