Caffeine Intake and Periodontal Treatment Outcomes

ConditionPeriodontitis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorHaoran Feng

About this trial

This study will explore whether caffeine intake can affect recovery after periodontal (gum) treatment.

Periodontitis is a common gum disease caused by bacteria. Even after treatment, some people may still have ongoing inflammation or changes in oral bacteria. Researchers want to know if daily caffeine intake, such as from coffee, may help improve this condition.

In this study, about 90 adults with periodontitis will receive standard periodontal treatment. Participants will be randomly assigned to one of three groups: no caffeine intake, low caffeine intake, or moderate caffeine intake. They will follow these instructions for about 6 months.

Researchers will collect saliva samples and check gum health at several time points after treatment. Saliva will be used to measure inflammation markers and to study changes in oral bacteria. Researchers will also record clinical gum conditions, such as gum pocket depth and bleeding.

The goal of this study is to understand whether caffeine intake can help reduce inflammation, improve oral bacteria balance, and support recovery after periodontal treatment. The results may help provide simple dietary advice to improve long-term gum health.

Eligibility criteria

Qualifiers

Adults aged 18 to 55 years.

Diagnosed with periodontitis according to the 2018 Classification of Periodontal and Peri-Implant Diseases and Conditions.

First visit for periodontal treatment and eligible for standard non-surgical periodontal therapy.

Willing and able to comply with the dietary intervention and scheduled follow-up visits.

Disqualifiers

Pregnant or breastfeeding women, or women planning pregnancy during the study period.

History of periodontal treatment within the previous 6 months.

Current smokers or tobacco users.

Use of antibiotics, anti-inflammatory drugs, immunosuppressive agents, or medications known to affect periodontal status within the previous 3 months.

Trial design

Treatments tested in this trial

  • No Caffeine Intake
  • Low Caffeine Intake
  • Moderate Caffeine Intake

Treatment groups

90 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Haoran Feng

Lead sponsor

Affiliated Stomatological Hospital of Xuzhou Medical University

Sponsor institution

Affiliated Stomatological Hospital of Xuzhou Medical University

Collaborator