Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 7
SponsorHillel Yaffe Medical Center

About this trial

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.

The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Newborn unfants born in Hillel Yaffe medical center

35 weeks of gestation or more

Blood culture was taken

Disqualifiers

Sepsis workup for other reason

34 weeks of gestation or less

Trial population

Newborn infants in Hillel Yaffe medical center

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • No intervention

    Other intervention

    No intervention

Treatment groups

6,300 Participants
are divided into 2 treatment groups
Group A: Before calculator1 intervention
Group B: With calculator1 intervention

Trial outcomes

Primary outcomes

1

Number of negative blood cultures out of all blood cultures

Total count of negative blood cultures out of all blood cultures in all patients in group

Time frame
during first week of life
2

Number of positive blood cultures

Total count of positive blood cultures in all patients in group

Time frame
during first week of life

Secondary outcomes

1

Cost of treatment

Total cost of Blood cultures + Blood counts + Antibiotic therpy in all patients in group

Time frame
during first week of life

Other outcomes

Sponsors and contacts

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