About this trial
Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.
The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Newborn unfants born in Hillel Yaffe medical center
35 weeks of gestation or more
Blood culture was taken
Disqualifiers
Sepsis workup for other reason
34 weeks of gestation or less
Trial population
Newborn infants in Hillel Yaffe medical center
Trial design
Cohort
Retrospective
Treatments tested in this trial
No intervention
Other interventionNo intervention
Treatment groups
Trial outcomes
Primary outcomes
Number of negative blood cultures out of all blood cultures
Total count of negative blood cultures out of all blood cultures in all patients in group
Number of positive blood cultures
Total count of positive blood cultures in all patients in group
Secondary outcomes
Cost of treatment
Total cost of Blood cultures + Blood counts + Antibiotic therpy in all patients in group
Sponsors and contacts
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