Calcification on CTCA of a CTO and PCI Outcomes
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSandwell & West Birmingham Hospitals NHS Trust
About this trial
A chronic total occlusion (CTO) is present in 15-20% of patients who are referred for invasive coronary angiography. CTO Percutaneous Coronary Intervention (PCI) procedure success rates have increased over the years and can be as high as 90% when performed by high-volume CTO operators.Procedurally, excess calcification in the CTO anatomy is one factor which makes it difficult to complete the procedure or obtain ideal stent expansion. Excess calcification is best identified by Computed Tomography Coronary Angiography (CTCA) rather than invasive angiography.
The investigators plan to retrospectively evaluate CTCA in patients who underwent CTO PCI and correlate calcification characteristics with CTO PCI outcomes and tools utilised for calcium modification.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients meeting all the below criteria will be included
≥18 years
Previous CTO PCI attempt in the last 5 years
Undergone CTCA either pre or post CTO PCI
Disqualifiers
Patients meeting any of the following criteria will be excluded
<18 years of age
Did not undergo CTCA
Inadequate/degraded CTCA images
Trial population
Patients with coronary CTO who underwent attempt at PCI and also underwent CTCA
Trial design
Design model
Other
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
100 Participants
are grouped into 1 trial groupGroup A: CTO patients who underwent attempted PCI
Trial outcomes
Primary outcomes
1
Correlation of characteristics of calcification with CTO PCI outcome (success or failure)
Success or failure
Time frame
up to 24 hoursSecondary outcomes
1
Utility of calcium modifying tools for the CTO PCI procedure and correlation with severity of calcification
Percentage of patients in whom any calcium modifying tool was used and the corelation of this with the severity of calcification.
Time frame
up to 24 hoursSponsors and contacts
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Source ClinicalTrials.gov