Calf Circumference Adjusted for Body Composition to Assess Muscle Mass
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Tartu
About this trial
Muscle mass is a critical indicator for malnutrition and sarcopenia assessment. Anthropometric measurements like calf circumference (CC) could be a simple and cost-effective alternative when gold standard methods are not available. However, CC is probably less accurate for estimating muscle mass in female patients and patients with obesity. This study investigates whether adjusting CC using mid-upper arm circumference (MUAC) improves muscle mass estimation in patients with obesity. If validated, this correction method would serve as a simple clinical tool for muscle mass assessment.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Patients of the internal medicine clinic for whom diagnostic bone density scanning (DEXA) has been requested by the physician normally responsible for the patient's care
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
150 Participants
are grouped into 1 trial groupGroup A: Patients undergoing bone density scanning at Tartu University Hospital
Trial outcomes
Primary outcomes
1
Accuracy of corrected calf circumference in estimating muscle mass
Accuracy of corrected calf circumference in estimating muscle mass in comparison to densitometry (DEXA) used as a gold standard
Time frame
15 monthsSecondary outcomes
1
Comparison of accuracy of corrected calf measurement results in female patients
Comparison of accuracy of results in female patients thought to be in greater need of correction
Time frame
15 months2
Comparison of accuracy of corrected calf measurement results in obese patients
Calf measurement results thought to be less reliable in obese patients
Time frame
15 months3
Quality of life with and without corrected results of anthropometry
Low muscle mass is associated with poor quality of life and may be estimated better with anthropometric corrections. Quality of life will be measured using the SarQoL tool designed to examine quality of life in sarcopenia (0-100 scale high being good)
Time frame
15 months4
Bone density estimated from corrected calf circumference
Bone density may be possible to estimate from corrected calf circumference
Time frame
15 monthsLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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