Calf Circumference Versus X-ray Absorptiometry in the Diagnosis of Sarcopenia in Elderly Hospitalized Patients

ConditionSarcopenia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age75+
SponsorCentre Hospitalier Régional d'Orléans

About this trial

This is a prospective single-center study to evaluate a diagnostic method. The main objective of the study is to evaluate the performance of calf circumference as a diagnostic method for sarcopenia in hospitalized elderly people, compared to a gold standard method which is X-ray absorptiometry. The study population are hospitalizing participants aged 75 years and older with an indication to search for sarcopenia.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age greater than or equal to 75 years

Hospitalization in a medical department or in the follow-up care or rehabilitation department of the Hospital Center of Orléans

Presence of an etiological criterion of undernutrition

Presence of a decrease in muscle strength

Disqualifiers

Presence of one of two phenotypic criteria for undernutrition other than sarcopenia, which are body mass index less than 22 kilogram per square meter and weight loss (≥ 5 percent over 1 month or ≥ 10 percent over 6 months or ≥10 percent compared with usual weight before the disease).

Refusal to participate in the study

Patient under legal protection

Impossible to perform X-ray absorptiometry (behavioral problems, functional constraints to climb on the DXA machine)

Trial design

Design model

Single group

Treatments tested in this trial

  • Dual-energy X-ray absorptiometry

    Radiation

    Whole body x-ray absorptiometry

Treatment groups

298 Participants
are divided into 1 treatment group
Group A: X-rayOther 1 intervention

Trial outcomes

Primary outcomes

1

Measurement of muscle mass using calf circumference

Measurement with a tape measure (in centimetres) of the maximum circumference of the calf

Time frame
Day 2
2

Measurement of muscle mass using X-ray absorptiometry

Measurement of appendicular mass by X-ray absorptiometry in kilograms

Time frame
Day 2

Secondary outcomes

1

Arm circumference

Measurement with a tape measure (in centimetres) of the maximum circumference of the arm

Time frame
Day 0
2

Circumference of the thigh

Measurement with a tape measure (in centimetres) of the maximum circumference of the thigh

Time frame
Day 0

Other outcomes

Sponsors and contacts

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