Calming Minds Study
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, Los Angeles
About this trial
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to:
1. Figure out what actually causes repetitive negative thinking to decrease when people use cognitive-behavioral therapy (CBT). 2. Find out which parts of RNT-focused CBT are the most important - the parts that truly make a difference in reducing RNT.
The main result we will look at is how much a person's repetitive negative thought patterns change from the start of the study to the end of treatment (16 weeks). We will measure this using the Perseverative Thinking Questionnaire at baseline and week 16.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Aged 18+ years
Able to provide a valid Imperial Valley College email address
Access to a suitable smartphone/device (iPhone 8+ running iOS 16.4 or higher, or Android version 8 or higher)
Access to internet
Disqualifiers
Concurrent psychotherapy
Self-reported current or past diagnosis or treatment for Psychosis
Self-reported current or past diagnosis or treatment for Bipolar disorder
Self-reported current or past diagnosis or currently receiving, or waiting to receive, treatment for substance abuse/dependence
Trial design
Design model
Factorial
Treatments tested in this trial
Be Specific
BehavioralDigital therapy lessons and coaching that emphasize skills in shifting from unhelpful abstract to helpful concrete processing style. Helping participants make changes to processing style to improve problem-solving and reduce emotional reactivity. Training concrete thinking to reduce RNT by increasing specific contextualized detail in description of events and plans.
Be Kind
BehavioralDigital therapy lessons and coaching that emphasize skills for replacing self-criticism with self-compassion. Helping participants shift toward a kinder, more validating way of relating to themselves to reduce the emotional patterns that sustain RNT. Training self-compassion skills to counter harsh self-evaluation and support emotional regulation.
Be Present
BehavioralDigital therapy lessons and coaching that emphasize skills for improving attention to present-moment experience. Helping participants redirect attention away from unhelpful mental ruminations by strengthening mindfulness and task absorption. Training present-moment awareness to interrupt the cognitive processes that maintain RNT by cultivating absorption in direct sensory experience.
Break Habit
BehavioralDigital therapy lessons and coaching that emphasize skills for disrupting repetitive negative thinking as a habitual mental behavior. Helping participants identify early warning signs, use stimulus-control strategies, form implementation intentions, and practice alternative responses to build more adaptive habits. Training new behavioral and cognitive routines to replace automatic RNT patterns.
Psychoeducation
BehavioralDigital therapy lessons and coaching that provide foundational information about repetitive negative thinking and why it occurs. Helping participants understand explanations for their symptoms and difficulties, which reduces the search for understanding, insight and certainty shown to drive RNT, and normalizes their experiences. This corresponds with the RF-CBT components of individualized rationale, psychoeducation, empathy and understanding.
Treatment groups
500 Participants
are divided into 16 treatment groups16
Treatment groupsSee each treatment group below.
Group A: Psychoeducation OnlyActive comparator 1 intervention
Group B: Be SpecificExperimental treatment 2 interventions
Group C: Be KindExperimental treatment 2 interventions
Group D: Break HabitExperimental treatment 2 interventions
Group E: Be PresentExperimental treatment 2 interventions
Group F: Be Specific + Be KindExperimental treatment 3 interventions
Group G: Be Specific + Be PresentExperimental treatment 3 interventions
Group H: Be Kind + Be PresentExperimental treatment 3 interventions
Group I: Be Specific + Be Kind + Be PresentExperimental treatment 4 interventions
Group J: Break Habit + Be SpecificExperimental treatment 3 interventions
Group K: Break Habit + Be KindExperimental treatment 3 interventions
Group L: Break Habit + Be Specific + Be KindExperimental treatment 4 interventions
Group M: Break Habit + Be PresentExperimental treatment 3 interventions
Group N: Break Habit + Be Specific+ Be PresentExperimental treatment 4 interventions
Group O: Break Habit + Be Kind + Be PresentExperimental treatment 4 interventions
Group P: ALLExperimental treatment 5 interventions
Trial outcomes
Primary outcomes
1
Change in Perseverative Thinking Questionnaire score from baseline to post-intervention
Change in repetitive negative thought as indexed by the Perseverative Thinking questionnaire
Time frame
Baseline, 16 weeksSecondary outcomes
1
Change in GAD-7 score from baseline to post-intervention
Change in anxiety measured with GAD-7
Time frame
Baseline, 16 weeks & 52 weeks2
Change in PHQ-9 score from baseline to post-intervention
Change in depression measured with PHQ-9
Time frame
Baseline, 16 weeks & 52 weeks3
Change in WEMWBS from baseline to post-intervention
Change in mental wellbeing measured with WEMWBS (Warwick-Edinburgh Mental Wellbeing Scale short-form)
Time frame
Baseline, 16 weeks & 52 weeks4
Change in RRS-Brooding subscale from baseline to post-intervention
Change in levels of rumination measured with RRS-Brooding subscale
Time frame
Baseline, 16 weeks & 52 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of California, Los Angeles
Lead sponsor
University of Exeter
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: