Candida Albicans in Syrian Patients With Periodontitis

ConditionsPeriodontal Disease Periodontal Diseases Periodontitis

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorAl-Hawash Private University

About this trial

Periodontitis is a significant oral health issue characterized by inflammation and destruction of the supporting structures of the teeth. Recent research has indicated that Candida albicans, a common fungal pathogen, may play a role in the exacerbation of periodontal diseases. This study aims to investigate the prevalence and impact of Candida albicans in Syrian patients diagnosed with periodontitis, contributing to a better understanding of its role in oral health within this population.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients aged 18 years and older.

Diagnosed with chronic periodontitis based on clinical examination (attachment loss, probing depth).

Consent to participate in the study.

Disqualifiers

Patients with systemic diseases affecting oral health (e.g., diabetes, immunosuppressive conditions).

Recent antibiotic or antifungal treatment within the last three months.

Trial population

Syrian patients with periodontitis at Al-Hawash Private University Dental Clinics

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Periodontal Assessment and Sample Collection from Subgingival Pockets
Diagnostic test
Clinical examination to assess periodontal status. Collection of subgingival plaque samples for microbiological analysis to identify Candida Albicans.

Treatment groups

100 Participants

are divided into 2 treatment groups

Group A: Syrian Patients With Periodontitis1 intervention

Group B: Syrian Individuals without Periodontal Disease1 intervention

Trial outcomes

Primary outcomes

Detection of Candida Species in Subgingival Samples

Time frame

At enrollment

Secondary outcomes

Periodontal Screening and Recording Index

Periodontal parameters are measured using the WHO probe by dividing the mouth into six sextants (three upper, three lower). The highest score in each sextant is recorded. Scoring from 0-4 is based on pocket depth, gingival health, and calculus presence. Scoring Criteria: 0: Healthy periodontium, black band visible. 1. Bleeding on probing (BOP), black band visible. 2. Calculus present, black band visible. 3. Pocket depth 3.5-5.5 mm (black band partially submerged). 4. Pocket depth \> 5.5 mm (black band entirely hidden).

Time frame

At enrollment

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Al-Hawash Private University

Lead sponsor

Source ClinicalTrials.gov

Apply now